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Positive Torsional Strain Causes the Formation of a Four-Way Junction at Replication Forks.
Chemtracts-Biochemistry and Molecular Biology
article original : http://www.jbc.org/content/276/4/2790
Research by L. Postow, C. Ullsperger, R.W. Keller, C. Bustamante, A.V. Vologodskii, and N.R. Cozzarelli, J. Biol. Chem. 2001, 276, 2790 Condensation and commentary by Alexander Bucka and Andrzej Stasiak, Universite ´ de Lausanne, Switzerland Purpose of the Study To demonstrate that positive torsional strain generated during DNA replication can lead to reversals of replication forks and, consequently can result in the formation of four-way DNA junctions
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