Primitive neuroectodermal tumor with choroid plexus differentiation.

Details

Serval ID
serval:BIB_1730C3A48558
Type
Article: article from journal or magazin.
Collection
Publications
Title
Primitive neuroectodermal tumor with choroid plexus differentiation.
Journal
Clinical Neuropathology
Author(s)
Janzer R.C., Kleihues P.
ISSN
0722-5091[print], 0722-5091[linking]
Publication state
Published
Issued date
1985
Volume
4
Number
3
Pages
93-98
Language
english
Abstract
A case of a cerebral juvenile undifferentiated round cell tumor with unusual formation of glandular structures is presented. The round cell component showed focal expression of glial fibrillary acidic protein, S-100 protein, neurofilament protein and neuron-specific enolase. The glandular part consisted of papillary epithelial structures with a central PAS-positive lumen. Ultrastructural findings supported the interpretation of these parts as choroid plexus. This route of differentiation was recognizable at the first operation at the age of 5 years and was much more prominent in the recurrence found 7 1/2 years later. The unusually benign course of this primitive neuroectodermal tumor (PNET) may be due to its intrinsic progressive tendency towards choroid plexus differentiation.
Keywords
Biopsy, Brain Neoplasms/pathology, Brain Neoplasms/surgery, Child, Child, Preschool, Humans, Male, Microscopy, Electron, Neoplasm Recurrence, Local, Neoplasms, Germ Cell and Embryonal/pathology, Neoplasms, Germ Cell and Embryonal/surgery, Occipital Lobe, Temporal Lobe
Pubmed
Create date
21/10/2010 8:38
Last modification date
20/08/2019 12:46
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