Peptide-MHC complexes assembled following multiple pathways: an opportunity for the design of vaccines and therapeutic molecules
Details
Serval ID
serval:BIB_14C4D758922E
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Peptide-MHC complexes assembled following multiple pathways: an opportunity for the design of vaccines and therapeutic molecules
Journal
Human Immunology
ISSN
0198-8859 (Print)
Publication state
Published
Issued date
05/1997
Volume
54
Number
2
Pages
137-47
Notes
Journal Article
Review --- Old month value: May
Review --- Old month value: May
Abstract
Antigen degradation and peptide loading to major histocompatibility complex class I and class II molecules are described with special emphasis on "noncanonical" pathways. Examples of specific peptide loading for measles proteins are provided. In addition, characterization of defined epitopes presented to T cells can lead to the design of products of special interest in medicine and, in particular, in development of vaccines.
Keywords
*Antigen Presentation
Antigens/immunology/metabolism
Epitopes/immunology
Histocompatibility Antigens Class I/immunology
Histocompatibility Antigens Class II/immunology
Humans
Major Histocompatibility Complex/*immunology
Measles virus/immunology
Models, Immunological
Peptides/*immunology
T-Lymphocytes/immunology
Vaccines/immunology
Viral Proteins/immunology
Pubmed
Web of science
Create date
24/01/2008 14:55
Last modification date
20/08/2019 12:43
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