P298 Comparison between clinical and patient-reported symptoms among Crohn's disease and ulcerative colitis patients

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State: Public
Version: Final published version
Serval ID
serval:BIB_1497244B88D8
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Poster: Summary – with images – on one page of the results of a researche project. The summaries of the poster must be entered in "Abstract" and not "Poster".
Collection
Publications
Institution
Title
P298 Comparison between clinical and patient-reported symptoms among Crohn's disease and ulcerative colitis patients
Title of the conference
Journal of Crohn's and Colitis
Author(s)
Pittet V., Maillard M.H., Rogler G., Michetti P.
Publisher
Oxford University Press (OUP)
Organization
Congress of ECCO: European of Crohn's and Colitis Organisation
Address
12th Congress of ECCO was held on February 15-18, 2017 at the CCIB in Barcelona.
ISSN
1873-9946
1876-4479
Publication state
Published
Issued date
01/02/2017
Volume
11
Number
S 1
Pages
S228-S229
Language
english
Notes
Poster presentations: Clinical: Diagnosis and outcome (2017)
Abstract
Background: There is no symptom-based patient-reported outcomes (PRO) measurement available in IBD. Disease scores contain a mixture of PRO and physician's observations and have shown serious limitations in clinical trials. Comparison between healthcare professionals (HCP) and patient (P) reports on scores' items is a first step toward disease scores refinement. In our IBD cohort study, we were able to collect P and HCP-reported symptoms independently. We assessed the agreement between both measures, and tested the correlation between the general well-being item (GWB) and two health-related quality of life (HRQoL) measures.
Methods: Between 2012 and 2015, we collected CDAI and MTWAI items 1) during follow-up medical visits, 2) through P self-reported follow-up questionnaire, except lab values. We compared items independently reported by HCP and P, stratified by diagnostic and Δt HCP-P reports. We calculated the Cohen's kappa (κ) statistic for agreement. A quadratic weight was applied for more severely serious disagreements. For EIM & complications, we computed a pooled κ based on the average between observed and expected probability of agreement over sub-items. A pooled κ was computed to summarize agreement over all examined variables. We also collected SF-36 and IBDQ scores. Pearson correlation coefficients r were calculated between both scores and GWB reports of HCP and P.
Results: 2427 reports could be evaluated (Δt: 537<1 month, 390 1–2, 1500 2–6), referring to 1385 patients (52% females, 58% CD).
Keywords
Gastroenterology, Crohn's disease, ulcerative colitis
Open Access
Yes
Create date
28/02/2017 15:18
Last modification date
20/08/2019 12:43
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