Sudden cardiac death in the young: A consensus statement on recommended practices for cardiac examination by pathologists from the Society for Cardiovascular Pathology.

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State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_139426CA3984
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Sudden cardiac death in the young: A consensus statement on recommended practices for cardiac examination by pathologists from the Society for Cardiovascular Pathology.
Journal
Cardiovascular pathology
Author(s)
Kelly K.L., Lin P.T., Basso C., Bois M., Buja L.M., Cohle S.D., d'Amati G., Duncanson E., Fallon J.T., Firchau D., Fishbein G., Giordano C., Leduc C., Litovsky S.H., Mackey-Bojack S., Maleszewski J.J., Michaud K., Padera R.F., Papadodima S.A., Parsons S., Radio S.J., Rizzo S., Roe S.J., Romero M., Sheppard M.N., Stone J.R., Tan C.D., Thiene G., van der Wal A.C., Veinot J.P.
ISSN
1879-1336 (Electronic)
ISSN-L
1054-8807
Publication state
Published
Issued date
2023
Peer-reviewed
Oui
Volume
63
Pages
107497
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Sudden cardiac death is, by definition, an unexpected, untimely death caused by a cardiac condition in a person with known or unknown heart disease. This major international public health problem accounts for approximately 15-20% of all deaths. Typically more common in older adults with acquired heart disease, SCD also can occur in the young where the cause is more likely to be a genetically transmitted process. As these inherited disease processes can affect multiple family members, it is critical that these deaths are appropriately and thoroughly investigated. Across the United States, SCD cases in those less than 40 years of age will often fall under medical examiner/coroner jurisdiction resulting in scene investigation, review of available medical records and a complete autopsy including toxicological and histological studies. To date, there have not been consistent or uniform guidelines for cardiac examination in these cases. In addition, many medical examiner/coroner offices are understaffed and/or underfunded, both of which may hamper specialized examinations or studies (e.g., molecular testing). Use of such guidelines by pathologists in cases of SCD in decedents aged 1-39 years of age could result in life-saving medical intervention for other family members. These recommendations also may provide support for underfunded offices to argue for the significance of this specialized testing. As cardiac examinations in the setting of SCD in the young fall under ME/C jurisdiction, this consensus paper has been developed with members of the Society of Cardiovascular Pathology working with cardiovascular pathology-trained, practicing forensic pathologists.
Keywords
Humans, Aged, Adult, Infant, Child, Preschool, Child, Adolescent, Young Adult, Pathologists, Death, Sudden, Cardiac/etiology, Death, Sudden, Cardiac/pathology, Heart Diseases/complications, Autopsy/methods, Heart, Cardiomyopathy, Death in the young, Forensic pathology heart examination, Genomics of sudden death, Hypertrophic cardiomyopathy, Sudden cardiac death, Sudden death, Sudden unexpected death in epilepsy
Pubmed
Open Access
Yes
Create date
17/11/2022 9:44
Last modification date
25/02/2023 7:46
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