ADL disability and death in dementia in a French population-based cohort: New insights with an illness-death model.

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Version: Final published version
License: Not specified
Serval ID
serval:BIB_134C6662E5A6
Type
Article: article from journal or magazin.
Collection
Publications
Title
ADL disability and death in dementia in a French population-based cohort: New insights with an illness-death model.
Journal
Alzheimer's & dementia
Author(s)
Delva F., Touraine C., Joly P., Edjolo A., Amieva H., Berr C., Rouaud O., Helmer C., Pérès K., Dartigues J.F.
ISSN
1552-5279 (Electronic)
ISSN-L
1552-5260
Publication state
Published
Issued date
08/2016
Peer-reviewed
Oui
Volume
12
Number
8
Pages
909-916
Language
english
Notes
Publication types: Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Transition to bathing or dressing disability is a milestone in the evolution of dementia. We examined the transition to disability in these specific activities and considered death to be a competitive event and age and sex to be prognostic factors.
From a large cohort of 570 incident dementia cases screened in two prospective population-based cohorts, the Paquid study, and the Three-City study, we estimated the probabilities of remaining nondisabled, becoming disabled in bathing or dressing, or dying after the diagnosis using an illness-death model.
On average, approximately half of the period (3 years) of living with dementia was free of disability. In women, a higher survival rate was associated with an average of 1 additional year with disability.
The joint prediction of death and disability in dementia by an illness-death model gives original and useful parameters for the prognosis and management of dementia.
Keywords
Activities of Daily Living, Age Factors, Aged, Aged, 80 and over, Cohort Studies, Community Health Planning, Dementia/epidemiology, Dementia/mortality, Disability Evaluation, Disabled Persons/statistics & numerical data, Female, France/epidemiology, Humans, Incidence, Male, Neurologic Examination, Probability, Sex Factors, Activities of daily living, Dementia, Follow-up studies, Prognosis
Pubmed
Web of science
Create date
23/08/2024 9:00
Last modification date
23/08/2024 9:34
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