'Tubular' epithelioid cell nevus: a new variant of Spitz's nevus

Détails

ID Serval
serval:BIB_12C34C54CF75
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
'Tubular' epithelioid cell nevus: a new variant of Spitz's nevus
Périodique
Journal of Cutaneous Pathology
Auteur(s)
Burg  G., Kempf  W., Hochli  M., Huwyler  T., Panizzon  R. G.
ISSN
0303-6987 (Print)
Statut éditorial
Publié
Date de publication
10/1998
Volume
25
Numéro
9
Pages
475-8
Notes
Case Reports
Journal Article --- Old month value: Oct
Résumé
The term Spitz's nevus refers to a large spectrum of nevi composed of spindle and/or epithelioid cells. We report on a hitherto undescribed tubular variant of a dermal epithelioid nevus, characterized by aggregates composed exclusively of cuboidal cells with the prominent feature of tubular or microcystic structures. Immunohistochemically, the epithelioid cells expressed melanocytic markers (S-100, NKI/C3) lacking markers for cytokeratin or carcinoembryonic antigen. The three-dimensional analysis of the lesions by confocal laser scanning microscopy revealed the structural configuration of tubular or microcystic empty spaces bordered by cuboidal nevus cells. This rare variant of epithelioid nevus is another example for the remarkable diversity of Spitz's nevi.
Mots-clé
Adult Humans Image Processing, Computer-Assisted Immunohistochemistry Male Microscopy, Confocal Nevus, Epithelioid and Spindle Cell/chemistry/*pathology S100 Proteins/analysis Skin Neoplasms/chemistry/*pathology Tumor Markers, Biological/analysis
Pubmed
Web of science
Création de la notice
25/01/2008 16:55
Dernière modification de la notice
20/08/2019 12:41
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