Visual Motion Area MT+/V5 Responds to Auditory Motion in Human Sight-Recovery Subjects.

Details

Serval ID
serval:BIB_1080F1D2F2C4
Type
Article: article from journal or magazin.
Collection
Publications
Title
Visual Motion Area MT+/V5 Responds to Auditory Motion in Human Sight-Recovery Subjects.
Journal
Journal of Neuroscience
Author(s)
Saenz M., Lewis L.B., Huth A.G., Fine I., Koch C.
ISSN
1529-2401 (Electronic)
ISSN-L
0270-6474
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
28
Number
20
Pages
5141-5148
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Abstract
Using functional magnetic resonance imaging, we found that cortical visual motion area MT+/V5 responded to auditory motion in two rare subjects who had been blind since early childhood and whose vision was partially recovered in adulthood. Visually normal control subjects did not show similar auditory responses. These auditory responses in MT+ were specific to motion compared with other complex auditory stimuli including frequency sweeps and speech. Thus, MT+ developed motion-specific responses to nonvisual input, suggesting that cross-modal plasticity can be influenced by the normal functional specialization of a cortical region. Regarding sight recovery after early blindness, our results further demonstrate that cross-modal responses coexist with regained visual responses within the visual cortex.
Keywords
Acoustic Stimulation, Adult, Age Factors, Auditory Perception/physiology, Blindness/physiopathology, Brain Mapping, Cerebrovascular Circulation/physiology, Female, Functional Laterality/physiology, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Motion Perception/physiology, Neural Pathways/anatomy & histology, Neural Pathways/physiology, Neuronal Plasticity/physiology, Observer Variation, Recovery of Function/physiology, Sound Localization/physiology, Temporal Lobe/anatomy & histology, Temporal Lobe/physiology, Visual Cortex/anatomy & histology, Visual Cortex/physiology, Visual Perception/physiology
Pubmed
Web of science
Open Access
Yes
Create date
06/03/2012 18:57
Last modification date
20/08/2019 13:37
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