Urinary 1-hydroxypyrene levels in offshore workers

Details

Serval ID
serval:BIB_100AEDC2327A
Type
Article: article from journal or magazin.
Collection
Publications
Title
Urinary 1-hydroxypyrene levels in offshore workers
Journal
International Archives of Occupational and Environmental Health
Author(s)
Hopf Nancy B., Kirkeleit Jorunn, Kramer Stacy L., Moen Bente, Succop Paul, Genter Mary B., Carreón Tania, Mack James, Talaska Glenn
ISSN
1432-1246 (Electronic)
ISSN-L
0340-0131
Publication state
Published
Issued date
01/2010
Peer-reviewed
Oui
Volume
83
Number
1
Pages
55-59
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
Publication Status: ppublish
Abstract
To compare differences in pre- and post-shift urinary 1-hydroxypyrene (1OHP) levels as a measure of internal dose of polycyclic aromatic hydrocarbons (PAHs) between two groups of oil production workers offshore assumed to be exposed to PAH, and to compare the exposed group to an unexposed control group.
Participants' (n = 42) urine samples, collected over a study period of three consecutive 12-h work days (pre-shift on the first day and post-shift on the third day), were analyzed using high performance liquid chromatography (HPLC) with fluorescence detection. Analysis of covariance was used in the statistical models.
(1) Post-shift 1OHP levels were significantly higher in the exposed workers compared to the controls. (2) Tank workers and process operators did not show statistically significant different post-shift 1OHP levels.
Altogether, this study indicates the presence of a low level PAH exposure among offshore oil production workers.

Keywords
Adult, Chromatography, High Pressure Liquid, Extraction and Processing Industry, Female, Humans, Male, Middle Aged, Occupational Exposure/analysis, Petroleum, Polycyclic Aromatic Hydrocarbons/analysis, Pyrenes/analysis
Pubmed
Web of science
Create date
07/10/2011 12:46
Last modification date
20/08/2019 13:36
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