Plasmacytoid dendritic cells: one-trick ponies or workhorses of the immune system?

Détails

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Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_0ECBA4BF3B77
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Editorial
Collection
Publications
Titre
Plasmacytoid dendritic cells: one-trick ponies or workhorses of the immune system?
Périodique
Nature Reviews. Immunology
Auteur(s)
Reizis B., Colonna M., Trinchieri G., Barrat F., Gilliet M.
ISSN
1474-1741 (Electronic)
ISSN-L
1474-1733
Statut éditorial
Publié
Date de publication
2011
Volume
11
Numéro
8
Pages
558-565
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural. Perspectives.
Publication Status: epublish
Résumé
Plasmacytoid dendritic cells (pDCs) were first described as interferon-producing cells and, for many years, their overlapping characteristics with both lymphocytes and classical dendritic cells (cDCs) created confusion over their exact ontogeny. In this Viewpoint article, Nature Reviews Immunology asks five leaders in the field to discuss their thoughts on the development and functions of pDCs--do these cells serve mainly as a major source of type I interferons or do they also make other important contributions to immune responses?
Mots-clé
Animals, Antigen Presentation/immunology, Autoimmune Diseases/immunology, Autoimmune Diseases/therapy, Cell Differentiation/immunology, Dendritic Cells/cytology, Dendritic Cells/immunology, Graft Rejection/immunology, Graft Rejection/prevention & control, Humans, Immune Tolerance/immunology, Inflammation/immunology, Interferon Type I/metabolism, Leukemia/immunology, Leukemia/therapy, Mice, Neoplasms/immunology, Neoplasms/therapy, T-Lymphocytes/cytology, T-Lymphocytes/immunology, Toll-Like Receptor 7/metabolism, Toll-Like Receptor 9/metabolism, Virus Diseases/immunology, Virus Diseases/therapy
Pubmed
Web of science
Open Access
Oui
Création de la notice
05/10/2011 11:43
Dernière modification de la notice
08/05/2019 14:27
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