Is the coiled body involved in nucleolar functions?

Détails

ID Serval
serval:BIB_0DCF85BE7754
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Is the coiled body involved in nucleolar functions?
Périodique
Experimental Cell Research
Auteur(s)
Malatesta M., Zancanaro C., Martin T.E., Chan E.K., Amalric F., Lührmann R., Vogel P., Fakan S.
ISSN
0014-4827 (Print)
ISSN-L
0014-4827
Statut éditorial
Publié
Date de publication
1994
Volume
211
Numéro
2
Pages
415-419
Langue
anglais
Résumé
Coiled bodies (CBs) are structural constituents observed in nuclei of most eukaryotic cells. They usually occur in the nucleoplasm as well as in contact with the nucleolar surface. In this work we studied the hepatocyte nuclei of hibernating dormice in order to investigate possible modifications of CBs along the seasonal cycle. CBs were abundant during hibernation and rapidly disappeared upon arousal from hibernation. Moreover, CBs were frequently found to be integrated into the nucleolar body. Immunocytochemical analyses showed that CBs contain nucleoplasmic as well as nucleolar RNA-processing factors, suggesting an "ambiguous" role for this organelle in the nuclear functions.
Mots-clé
Animals, Antibodies, Monoclonal, Cell Nucleolus/metabolism, Cell Nucleolus/ultrastructure, Chromosomal Proteins, Non-Histone/metabolism, Hibernation, Liver/metabolism, Liver/ultrastructure, Microscopy, Immunoelectron, Nuclear Proteins/immunology, Nuclear Proteins/metabolism, RNA Precursors/metabolism, Ribonucleoproteins, Small Nuclear/metabolism, Rodentia
Pubmed
Web of science
Création de la notice
24/01/2008 18:32
Dernière modification de la notice
03/03/2018 13:40
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