Prevalence and clinical importance of mesenteric venous thrombosis in the Swiss Inflammatory Bowel Disease Cohort

Détails

ID Serval
serval:BIB_0DBF24CC0B2A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Prevalence and clinical importance of mesenteric venous thrombosis in the Swiss Inflammatory Bowel Disease Cohort
Périodique
Ajr. American Journal of Roentgenology
Auteur(s)
Violi N.V., Vietti Violi N., Schoepfer A.M., Fournier N., Guiu B., Bize P., Denys A.
Collaborateur(s)
Swiss Inflammatory Bowel Disease Cohort Study Group
Contributeur(s)
Bauerfeind P., Beglinger C., Begré S., Bengoa J., Binek J., Boller D., Borovicka J., Braegger C., Burnand B., Camara R., Criblez D., Degen L., Delarive J., de Saussure P., Ehmann T., El Wafa A., Engelmann M., Felley C., Frei A., Frei R., Fried M., Friedt M., Froehlich F., Gallot-Lavallée S., Gerlach T., Geyer M., Girardin M., Goetze O., Haack H., Hediger S., Hengstler P., Heyland K., Janiak P., Juillerat P., Kessler Brondolo V., Knoblauch C., Kullak-Ublick GA., Maillard M., Manz M., Meier R., Meyenberger C., Michetti P., Mottet C., Müller C., Müllhaupt B., Nicolet T., Nydegger A., Pache I., Piccoli F., Pilz J., Pittet V., Rentsch R., Rey JP., Rihs S., Rogler D., Rogler G., Sagmeister M., Sauter B., Schaub N., Schibli S., Schoepfer AM., Seibold F., Spalinger J., Stadler P., Steuerwald M., Straumann A., Sulz M., Tempia-Caliera M., Thorens£££Joël£££ J. , Vader JP., Vavricka SR., Vögtlin J., Von Känel R., Wachter G., Wermuth J., Wiesel P.
ISSN
1546-3141 (Electronic)
ISSN-L
0361-803X
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
203
Numéro
1
Pages
62-69
Langue
anglais
Résumé
OBJECTIVE: The purpose of this study was to evaluate the prevalence of mesenteric venous thrombosis (MVT) in the Swiss Inflammatory Bowel Disease Cohort Study and to correlate MVT with clinical outcome.
MATERIALS AND METHODS: Abdominal portal phase CT was used to examine patients with inflammatory bowel disease (IBD). Two experienced abdominal radiologists retrospectively analyzed the images, focusing on the superior and inferior mesenteric vein branches and looking for signs of acute or chronic thrombosis. The location of abnormalities was registered. The presence of MVT was correlated with IBD-related radiologic signs and complications.
RESULTS: The cases of 160 patients with IBD (89 women, 71 men; Crohn disease [CD], 121 patients; ulcerative colitis [UC], 39 patients; median age at diagnosis, 27 years for patients with CD, 32 years for patients with UC) were analyzed. MVT was detected in 43 patients with IBD (26.8%). One of these patients had acute MVT; 38, chronic MVT; and four, both. The prevalence of MVT did not differ between CD (35/121 [28.9%]) and UC (8/39 [20.5%]) (p = 0.303). The location of thrombosis was different between CD and UC (CD, jejunal or ileal veins only [p = 0.005]; UC, rectocolic veins only [p = 0.001]). Almost all (41/43) cases of thrombosis were peripheral. MVT in CD patients was more frequently associated with bowel wall thickening (p = 0.013), mesenteric fat hypertrophy (p = 0.005), ascites (p = 0.002), and mesenteric lymph node enlargement (p = 0.036) and was associated with higher rate of bowel stenosis (p < 0.001) and more intestinal IBD-related surgery (p = 0.016) in the outcome. Statistical analyses for patients with UC were not relevant because of the limited population (n = 8).
CONCLUSION: MVT is frequently found in patients with IBD. Among patients with CD, MVT is associated with bowel stenosis and CD-related intestinal surgery.
Mots-clé
Adult, Contrast Media/diagnostic use, Female, Humans, Inflammatory Bowel Diseases/complications, Male, Mesenteric Veins, Prevalence, Retrospective Studies, Switzerland/epidemiology, Tomography, X-Ray Computed/methods, Venous Thrombosis/epidemiology, Venous Thrombosis/etiology
Pubmed
Web of science
Création de la notice
22/11/2014 10:54
Dernière modification de la notice
03/03/2018 13:40
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