Article: article from journal or magazin.
Coordinated polar localization of auxin efflux carrier PIN1 by GNOM ARF GEF.
The plant hormone auxin is transported in a polar manner along the shoot-root axis, which requires efflux carriers such as PIN1. Asymmetric localization of PIN1 develops from a random distribution in Arabidopsis early embryogenesis. Coordinated polar localization of PIN1 is defective in gnom embryos. GNOM is a membrane-associated guanine-nucleotide exchange factor on ADP-ribosylation factor G protein (ARF GEF). Thus, GNOM-dependent vesicle trafficking may establish cell polarity, resulting in polar auxin transport.
ADP-Ribosylation Factors/metabolism, Arabidopsis/cytology, Arabidopsis/embryology, Arabidopsis Proteins, Biological Transport, Brefeldin A/pharmacology, Cell Membrane/metabolism, Cell Polarity, Cytosol/metabolism, Guanine Nucleotide Exchange Factors/chemistry, Guanine Nucleotide Exchange Factors/genetics, Indoleacetic Acids/metabolism, Membrane Proteins/metabolism, Membrane Transport Proteins, Plant Roots/growth & development, Plant Roots/metabolism, Protein Conformation, Recombinant Proteins/metabolism, Seeds/cytology, Seeds/metabolism, Solubility, Subcellular Fractions/metabolism
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