Article: article from journal or magazin.
Synergistic epistasis and alternative hypotheses.
Journal of Evolutionary Biology
discussion pp. 1402-1404
Inbreeding generally results in deleterious shifts in mean fitness. If the fitness response to increasing inbreeding coefficient is non-linear, this suggests a contribution of epistasis to inbreeding depression. In a cross-breeding experiment, Salathe & Ebert (2003. J. Evol. Biol. 16: 976-985) tested and found the presence of this non-linearity in Daphnia magna. They argue that epistatic interactions cause this non-linearity. We argue here that their experimental protocol does not allow disentangling the effect of synergistic epistasis from two alternative hypotheses, namely hybrid vigour and statistical non-independence of data.
Animals, Daphnia, Epistasis, Genetic, Genetics, Population, Hybridization, Genetic, Inbreeding, Models, Genetic, Phenotype, Selection, Genetic
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