Neuroendocrine neoplasms of the head and neck and olfactory neuroblastoma. Diagnosis and classification.

Details

Serval ID
serval:BIB_0CC8A83426D8
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Neuroendocrine neoplasms of the head and neck and olfactory neuroblastoma. Diagnosis and classification.
Journal
Pathologica
Author(s)
Uccella S., Ottini G., Facco C., Maragliano R., Asioli S., Sessa F., La Rosa S.
ISSN
0031-2983 (Print)
ISSN-L
0031-2983
Publication state
Published
Issued date
03/2017
Peer-reviewed
Oui
Volume
109
Number
1
Pages
14-30
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Neuroendocrine neoplasms (NENs) of the head and neck are a rare group of heterogeneous epithelial neoplastic proliferations arising in virtually all of the different organs of this region, particularly in the nasal cavity, the paranasal sinuses, the nasopharynx, the larynx, the salivary glands, and the middle ear. They encompass a wide spectrum of entities ranging from very indolent neuroendocrine tumors to highly aggressive neuroendocrine carcinomas. They may represent a challenge for radiologists, oncologists, and pathologists and a correct diagnosis is crucial for the management of patients. The nomenclature and classification of cervicocephalic NENs is currently under debate and for this reason a different diagnostic terminology has been used over the years, creating confusions among clinicians and pathologists. Olfactory neuroblastoma is a rare neuroectodermal neoplasm arising in the nasal cavity showing some challenging diagnostic aspects. In this review we give an update of the more relevant criteria for diagnosing head and neck NENs and olfactory neuroblastomas focusing on the critical use of morphological parameters and immunohistochemical staining.
Keywords
Carcinoma, Neuroendocrine, Esthesioneuroblastoma, Olfactory/diagnosis, Esthesioneuroblastoma, Olfactory/therapy, Humans, Nasal Cavity, Neuroendocrine Tumors, Nose Neoplasms/diagnosis, Nose Neoplasms/therapy, Carcinoid, Head and neck, Neuroendocrine carcinoma, Neuroendocrine neoplasm, Olfactory neuroblastoma
Pubmed
Web of science
Create date
22/06/2017 12:38
Last modification date
20/08/2019 12:34
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