Lack of a role of circulating bradykinin in the blood pressure response to acute angiotensin converting enzyme inhibition in rats.

Détails

ID Serval
serval:BIB_0C44BDA8E32D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Lack of a role of circulating bradykinin in the blood pressure response to acute angiotensin converting enzyme inhibition in rats.
Périodique
Agents and Actions. Supplements
Auteur(s)
Aubert J.F., Waeber B., Nussberger J., Vavrek R., Stewart J.M., Brunner H.R.
ISSN
0379-0363
Statut éditorial
Publié
Date de publication
1987
Volume
22
Pages
349-354
Langue
anglais
Résumé
The role of circulating bradykinin in blood pressure regulation was investigated in conscious normotensive rats using a competitive antagonist of bradykinin. The acute blood pressure effect of this antagonist was also evaluated after inhibition of angiotensin converting enzyme with captopril and during simultaneous infusion of exogenous angiotensin II. No evidence was found for a role of circulating bradykinin in rats studied under normal conditions. Endogenous bradykinin seemed however involved in blood pressure control during angiotensin II infusion. Acute angiotensin converting enzyme inhibition had no influence on the blood pressure response to the bradykinin antagonist.
Mots-clé
Angiotensin II, Animals, Blood Pressure, Bradykinin, Captopril, Male, Rats, Rats, Inbred Strains
Pubmed
Web of science
Création de la notice
05/03/2008 17:39
Dernière modification de la notice
03/03/2018 13:37
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