A control flow prototype for a dose recommending device for chronic myeloid leukemia patients

Details

Serval ID
serval:BIB_0B7B08FD50EA
Type
Inproceedings: an article in a conference proceedings.
Collection
Publications
Institution
Title
A control flow prototype for a dose recommending device for chronic myeloid leukemia patients
Title of the conference
4th Workshop on Medical Cyber Physical Systems
Author(s)
Simalatsar A., Wenqi Y., Dechao S., Gotta V., Widmer N., De Micheli G.
Address
Philadelphia, Pennsylvania, United-States, April 8, 2013
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Language
english
Abstract
In this paper we present a prototype of a control flow for an a posteriori drug dose adaptation for Chronic Myelogenous Leukemia (CML) patients. The control flow is modeled using Timed Automata extended with Tasks (TAT) model. The feedback loop of the control flow includes the decision-making process for drug dose adaptation. This is based on the outputs of the body response model represented by the Support Vector Machine (SVM) algorithm for drug concentration prediction. The decision is further checked for conformity with the dose level rules of a medical guideline. We also have developed an automatic code synthesizer for the icycom platform as an extension of the TIMES tool.
Create date
16/04/2013 18:06
Last modification date
20/08/2019 13:33
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