Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska, P.; Alitalo, K.; Allen, E.; Anisimov, A.; Aplin, A.C.; Auerbach, R.; Augustin, H.G.; Bates, D.O.; van Beijnum, J.R.; Bender, RHF; Bergers, G.; Bikfalvi, A.; Bischoff, J.; Böck, B.C.; Brooks, P.C.; Bussolino, F.; Cakir, B.; Carmeliet, P.; Castranova, D.; Cimpean, A.M.; Cleaver, O.; Coukos, G.; Davis, G.E.; De Palma, M.; Dimberg, A.; Dings, RPM; Djonov, V.; Dudley, A.C.; Dufton, N.P.; Fendt, S.M.; Ferrara, N.; Fruttiger, M.; Fukumura, D.; Ghesquière, B.; Gong, Y.; Griffin, R.J.; Harris, A.L.; Hughes, CCW; Hultgren, N.W.; Iruela-Arispe, M.L.; Irving, M.; Jain, R.K.; Kalluri, R.; Kalucka, J.; Kerbel, R.S.; Kitajewski, J.; Klaassen, I.; Kleinmann, H.K.; Koolwijk, P.; Kuczynski, E.; Kwak, B.R.; Marien, K.; Melero-Martin, J.M.; Munn, L.L.; Nicosia, R.F.; Noel, A.; Nurro, J.; Olsson, A.K.; Petrova, T.V.; Pietras, K.; Pili, R.; Pollard, J.W.; Post, M.J.; Quax, PHA; Rabinovich, G.A.; Raica, M.; Randi, A.M.; Ribatti, D.; Ruegg, C.; Schlingemann, R.O.; Schulte-Merker, S.; Smith, LEH; Song, J.W.; Stacker, S.A.; Stalin, J.; Stratman, A.N.; Van de Velde, M.; van Hinsbergh, VWM; Vermeulen, P.B.; Waltenberger, J.; Weinstein, B.M.; Xin, H.; Yetkin-Arik, B.; Yla-Herttuala, S.; Yoder, M.C.; Griffioen, A.W.

doi:10.1007/s10456-018-9613-x

Consensus guidelines for the use and interpretation of angiogenesis assays.

Details

Download: 29766399_BIB_0B60945B0B6F.pdf (6896.55 [Ko])
State: Public
Version: Author's accepted manuscript
License: CC BY 4.0

Serval ID

serval:BIB_0B60945B0B6F

Type

Article: article from journal or magazin.

Publication sub-type

Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.

Collection

Publications

Institution

UNIL/CHUV

Title

Consensus guidelines for the use and interpretation of angiogenesis assays.

Journal

Angiogenesis

Author(s)

Nowak-Sliwinska P., Alitalo K., Allen E., Anisimov A., Aplin A.C., Auerbach R., Augustin H.G., Bates D.O., van Beijnum J.R., Bender RHF, Bergers G., Bikfalvi A., Bischoff J., Böck B.C., Brooks P.C., Bussolino F., Cakir B., Carmeliet P., Castranova D., Cimpean A.M., Cleaver O., Coukos G., Davis G.E., De Palma M., Dimberg A., Dings RPM, Djonov V., Dudley A.C., Dufton N.P., Fendt S.M., Ferrara N., Fruttiger M., Fukumura D., Ghesquière B., Gong Y., Griffin R.J., Harris A.L., Hughes CCW, Hultgren N.W., Iruela-Arispe M.L., Irving M., Jain R.K., Kalluri R., Kalucka J., Kerbel R.S., Kitajewski J., Klaassen I., Kleinmann H.K., Koolwijk P., Kuczynski E., Kwak B.R., Marien K., Melero-Martin J.M., Munn L.L., Nicosia R.F., Noel A., Nurro J., Olsson A.K., Petrova T.V., Pietras K., Pili R., Pollard J.W., Post M.J., Quax PHA, Rabinovich G.A., Raica M., Randi A.M., Ribatti D., Ruegg C., Schlingemann R.O., Schulte-Merker S., Smith LEH, Song J.W., Stacker S.A., Stalin J., Stratman A.N., Van de Velde M., van Hinsbergh VWM, Vermeulen P.B., Waltenberger J., Weinstein B.M., Xin H., Yetkin-Arik B., Yla-Herttuala S., Yoder M.C., Griffioen A.W.

ISSN

1573-7209 (Electronic)

ISSN-L

0969-6970

Publication state

Published

Issued date

08/2018

Peer-reviewed

Oui

Volume

Number

Pages

425-532

Language

english

Notes

Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish

Abstract

The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions. Angiogenesis undergoes multiple discrete steps that can be individually evaluated and quantified by a large number of bioassays. These independent assessments hold advantages but also have limitations. This article describes in vivo, ex vivo, and in vitro bioassays that are available for the evaluation of angiogenesis and highlights critical aspects that are relevant for their execution and proper interpretation. As such, this collaborative work is the first edition of consensus guidelines on angiogenesis bioassays to serve for current and future reference.

Keywords

Animals, Biological Assay/instrumentation, Biological Assay/methods, Guidelines as Topic, Humans, Mice, Neoplasms/blood supply, Neoplasms/metabolism, Neoplasms/pathology, Neovascularization, Pathologic/metabolism, Neovascularization, Pathologic/pathology, Angiogenesis, Aortic ring, Chorioallantoic membrane (CAM), Corneal angiogenesis, Endothelial cell migration, Hindlimb ischemia, Intussusceptive angiogenesis, Microfluidic, Myocardial angiogenesis, Plug assay, Proliferation, Recombinant proteins, Retinal vasculature, Tip cells, Vascular network, Vessel co-option, Zebrafish

URN

urn:nbn:ch:serval-BIB_0B60945B0B6F2

OAI-PMH

oai:serval.unil.ch:BIB_0B60945B0B6F

DOI

10.1007/s10456-018-9613-x

Pubmed

29766399

Web of science

000438644400001

Open Access

Yes