In 2018, many innovations have appeared in the field of HIV. From the laboratory to self-test sold in pharmacy, all aspects of the HIV spectrum are affected. These new features not only concern HIV infected patients and their specialists but all health workers. The constant improvement of HIV care and prevention is essential to reach the ambitious goal set by UNAIDS : 90‑90‑90. By 2020, 90 % of all people living with HIV know their status, 90 % of all people diagnosed with HIV receive antiretroviral treatment and 90 % of all people receiving therapy are virally suppressed. In this article we review what we thought were the most significant innovations of 2018 : self-testing, newly approved 4th generation screening tests with a shortened 6-week window period, use of PrEP, new treatments and the latest research about reservoirs.