Extended endoscopic endonasal approach to clival and paraclival tumors: Indications and limits.
Details
Serval ID
serval:BIB_0A545B50C89F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Extended endoscopic endonasal approach to clival and paraclival tumors: Indications and limits.
Journal
Neuro-Chirurgie
ISSN
1773-0619 (Electronic)
ISSN-L
0028-3770
Publication state
Published
Issued date
03/2016
Peer-reviewed
Oui
Volume
62
Number
3
Pages
136-145
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
To report our experience with the Extended endoscopic endonasal approach (EEEA) for clival and paraclival tumors.
Retrospective analysis of a consecutive series of patients.
Eleven patients were considered: 3 chordomas, 3 meningiomas, 3 metastatic lesions, one chondroma and one chondrosarcoma. Gross total resection (GTR) was achieved in all chordomas and in chondromas with patients free of disease at the last follow-up. The chondrosarcoma was first operated on using a transfacial approach and endoscopy was performed for local progression with subtotal resection. The meningiomas were treated by a combination of transcranial and endoscopic approach due to their extension. The resection was subtotal and the residue treated by radiosurgery. Two patients with rhinopharyngeal carcinoma underwent palliative debulking. One metastatic melanoma that underwent GTR experienced remission. Two patients had postoperative cranial nerve palsy. No other complications were observed.
EEEA allows a direct access to the skull base. Through a minimal access, it limits the incidence of neurological morbidities. For midline epidural clival tumors, EEEA allows a total excision. It also offers an excellent access to the clival component of intradural lesions. A combined approach permits good tumor control with minimal complications.
Retrospective analysis of a consecutive series of patients.
Eleven patients were considered: 3 chordomas, 3 meningiomas, 3 metastatic lesions, one chondroma and one chondrosarcoma. Gross total resection (GTR) was achieved in all chordomas and in chondromas with patients free of disease at the last follow-up. The chondrosarcoma was first operated on using a transfacial approach and endoscopy was performed for local progression with subtotal resection. The meningiomas were treated by a combination of transcranial and endoscopic approach due to their extension. The resection was subtotal and the residue treated by radiosurgery. Two patients with rhinopharyngeal carcinoma underwent palliative debulking. One metastatic melanoma that underwent GTR experienced remission. Two patients had postoperative cranial nerve palsy. No other complications were observed.
EEEA allows a direct access to the skull base. Through a minimal access, it limits the incidence of neurological morbidities. For midline epidural clival tumors, EEEA allows a total excision. It also offers an excellent access to the clival component of intradural lesions. A combined approach permits good tumor control with minimal complications.
Keywords
Adult, Antineoplastic Agents/therapeutic use, Combined Modality Therapy, Cranial Fossa, Posterior/surgery, Cranial Irradiation, Cranial Nerve Diseases/epidemiology, Cranial Nerve Diseases/etiology, Endoscopy/methods, Female, Humans, Male, Middle Aged, Monitoring, Intraoperative, Nasal Cavity, Postoperative Complications/epidemiology, Radiosurgery, Remission Induction, Retrospective Studies, Skull Base Neoplasms/drug therapy, Skull Base Neoplasms/radiotherapy, Skull Base Neoplasms/secondary, Skull Base Neoplasms/surgery, Young Adult
Pubmed
Create date
31/05/2016 16:45
Last modification date
20/08/2019 12:32