Laparoscopic versus ultrasound-guided transversus abdominis plane block in colorectal surgery: a non-inferiority, multicentric randomized double-blinded clinical trial.

Details

Serval ID
serval:BIB_0A47E0E9F08F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Laparoscopic versus ultrasound-guided transversus abdominis plane block in colorectal surgery: a non-inferiority, multicentric randomized double-blinded clinical trial.
Journal
Colorectal disease
Author(s)
La Regina D., Popeskou S.G., Saporito A., Gaffuri P., Tasciotti E., Dossi R., Christoforidis D., Mongelli F.
ISSN
1463-1318 (Electronic)
ISSN-L
1462-8910
Publication state
Published
Issued date
09/2023
Peer-reviewed
Oui
Volume
25
Number
9
Pages
1921-1928
Language
english
Notes
Publication types: Equivalence Trial ; Journal Article ; Multicenter Study ; Randomized Controlled Trial
Publication Status: ppublish
Abstract
The aim of this study was to assess if laparoscopic-assisted transversus abdominis plane (TAP) block (L-TAPB) is as efficient as ultrasound-guided TAP block (U-TAPB) in postoperative pain control.
In all, 112 patients scheduled for elective laparoscopic colon resection from February 2018 to December 2021 at two Swiss hospitals were included and randomized in a 1:1 ratio before surgery with either L-TAPB or U-TAPB. The primary end-point was the non-inferiority of the L-TAPB compared to U-TAPB with regard to the total opioid consumption within the first 24 h after surgery. Data regarding patients' characteristics, opioid consumption, pain on the visual analogue scale, operative and anaesthesia induction time, complications and length of stay were collected and analysed.
Fifty-five patients were allocated to the L-TAPB and fifty-seven to the U-TAPB. No significant difference was found in the overall dose of opioids within 24 h, and the non-inferiority of the L-TAPB was confirmed. There were almost twice as many patients in the L-TAPB group requesting opioid reserves compared to the U-TAPB group (54.5% vs. 29.8%, P = 0.008). The anaesthesia induction time was significantly longer in the U-TAPB group (17 ± 11 min vs. 23 ± 12 min, P = 0.014). For all other variables (pain on the visual analogue scale, opioid consumption, need of epidural analgesia, operating time, postoperative complications and hospital stay) no statistically significant difference between the L-TAPB and the U-TAPB groups was noted.
Our results showed the non-inferiority of the laparoscopic delivery compared to ultrasound-guided administration of the TAP block, with the advantage of not affecting anaesthesia times.
2017-02017 CE 3294, ClinicalTrials.gov identifier NCT04575233.
Keywords
Humans, Abdominal Muscles/diagnostic imaging, Analgesics, Opioid/therapeutic use, Colectomy/methods, Colorectal Surgery, Laparoscopy/methods, Pain, Postoperative/drug therapy, Pain, Postoperative/etiology, Ultrasonography, Interventional, TAP block, colorectal, postoperative pain, surgery, transversus abdominis plane
Pubmed
Web of science
Create date
03/08/2023 13:31
Last modification date
19/12/2023 7:15
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