Leptospirose famitiate apres rafting en Thaïlande [Leptospirosis in a family after whitewater rafting in Thailand].

Details

Serval ID
serval:BIB_0A47AE435C80
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Leptospirose famitiate apres rafting en Thaïlande [Leptospirosis in a family after whitewater rafting in Thailand].
Journal
Revue Médicale Suisse
Author(s)
Gallardo C., Williams-Smith J., Jaton K., Asner S., Cheseaux J.J., Troillet N., Manuel O., Berthod D.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
04/2015
Volume
11
Number
470
Pages
872-876
Language
french
Notes
Publication types: Case Reports ; English Abstract ; Journal Article
Publication Status: ppublish
Abstract
Leptospirosis is a zoonosis found worldwide, with an incidence that is approximately 10 times higher in the tropics than in temperate regions. The main reservoir of leptospirosis is the rat and human infection usually results from exposure to infected animal urine or tissues. Only 10% of cases are symptomatic. We present here two confirmed and two probable cases of leptospirosis in a family returning from whitewater rafting in Thailand, illustrating the wide variety of the clinical manifestations of this infection. Two of the patients were hospitalized and presented a probable Jarisch-Herxheimer reaction after initiation of beta-lactam therapy. The two others patients were treated empirically with doxycycline. We discuss here some relevant aspects of the epidemiology, clinical manifestations, therapy and the challenge of an early diagnosis of leptospirosis.
Keywords
Adolescent, Adult, Animals, Anti-Bacterial Agents/adverse effects, Anti-Bacterial Agents/therapeutic use, Doxycycline/therapeutic use, Female, Humans, Leptospirosis/diagnosis, Leptospirosis/drug therapy, Male, Recreation, Rivers, Thailand/epidemiology, Travel, Zoonoses/diagnosis, Zoonoses/drug therapy, beta-Lactams/adverse effects, beta-Lactams/therapeutic use
Pubmed
Create date
06/09/2015 19:42
Last modification date
20/08/2019 12:32
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