Impulsivity in early psychosis: A complex link with violent behaviour and a target for intervention.

Détails

ID Serval
serval:BIB_09FECFB51A73
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Impulsivity in early psychosis: A complex link with violent behaviour and a target for intervention.
Périodique
European psychiatry
Auteur(s)
Moulin V., Golay P., Palix J., Baumann P.S., Gholamrezaee M.M., Azzola A., Gasser J., Do K.Q., Alameda L., Conus P.
ISSN
1778-3585 (Electronic)
ISSN-L
0924-9338
Statut éditorial
Publié
Date de publication
03/2018
Peer-reviewed
Oui
Volume
49
Pages
30-36
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
Violent behaviour (VB) occurs in first episode of schizophrenia and can have devastating impact both on victims and patients themselves. A better knowledge of the underlying mechanisms of VB may pave the way to preventive treatments.
1) To explore the nature of the link between impulsivity and VB in early psychosis (EP) patients; 2) To explore the interactions between impulsivity and substance abuse, insight, and positive symptoms, the main dynamic risk factors of VB described to date.
Post hoc analysis of data acquired in the frame of a 36-months EP cohort study. A total of 265 EP patients, aged 18 to 35, treated at TIPP (Treatment and early Intervention in Psychosis Program), at the Department of Psychiatry in Lausanne, Switzerland, were included in the study. Logistic regression analyzes were performed as well as mediation analysis and interaction analysis RESULTS: Our data suggest that impulsivity is a predictor of VB when analyzed independently and as part of a multi-factorial model. Impulsivity continues to differentiate violent patients from non-violent ones at the end of the program. In addition, the relationship between impulsivity and VB is not mediated by substance abuse. Finally, the effect of impulsivity on the probability of VB is potentiated by the interaction of different levels of insight and positive symptoms.
Early intervention strategies in psychotic disorders should include evaluation of impulsivity considering it is linked to increased risk of VB and may respond to treatment.
Mots-clé
Adult, Cohort Studies, Comorbidity, Female, Follow-Up Studies, Humans, Impulsive Behavior, Logistic Models, Longitudinal Studies, Male, Prospective Studies, Psychotic Disorders/epidemiology, Psychotic Disorders/psychology, Psychotic Disorders/therapy, Risk Factors, Schizophrenia/epidemiology, Schizophrenia/therapy, Surveys and Questionnaires, Switzerland/epidemiology, Violence/prevention & control, Violence/psychology, Violence/statistics & numerical data, Young Adult, Early psychosis, Impulsivity, Schizophrenia, Violence, Violent behavior
Pubmed
Web of science
Création de la notice
11/12/2017 11:16
Dernière modification de la notice
20/08/2019 13:32
Données d'usage