Biological functions of lymphatic vessels.

Details

Serval ID
serval:BIB_0975AC40A1DE
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Biological functions of lymphatic vessels.
Journal
Science
Author(s)
Petrova T.V., Koh G.Y.
ISSN
1095-9203 (Electronic)
ISSN-L
0036-8075
Publication state
Published
Issued date
10/07/2020
Peer-reviewed
Oui
Volume
369
Number
6500
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Abstract
The general functions of lymphatic vessels in fluid transport and immunosurveillance are well recognized. However, accumulating evidence indicates that lymphatic vessels play active and versatile roles in a tissue- and organ-specific manner during homeostasis and in multiple disease processes. This Review discusses recent advances to understand previously unidentified functions of adult mammalian lymphatic vessels, including immunosurveillance and immunomodulation upon pathogen invasion, transport of dietary fat, drainage of cerebrospinal fluid and aqueous humor, possible contributions toward neurodegenerative and neuroinflammatory diseases, and response to anticancer therapies.
Keywords
Animals, Central Nervous System/immunology, Central Nervous System Infections/immunology, Cerebrospinal Fluid/immunology, Encephalitis/immunology, Homeostasis/immunology, Humans, Immunologic Surveillance, Intestines/immunology, Lymphatic Vessels/immunology, Lymphatic Vessels/microbiology, Mice, Neoplasms/immunology, Neurodegenerative Diseases/immunology
Pubmed
Create date
24/07/2020 10:43
Last modification date
15/08/2020 5:26
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