Outcomes of disconnective surgery in intractable pediatric hemispheric and subhemispheric epilepsy.

Détails

Ressource 1Télécharger: BIB_0967A80E158E.P001.pdf (5228.22 [Ko])
Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_0967A80E158E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Outcomes of disconnective surgery in intractable pediatric hemispheric and subhemispheric epilepsy.
Périodique
International Journal of Pediatrics
Auteur(s)
Thomas S.G., Chacko A.G., Thomas M.M., Babu K.S., Russell P.S., Daniel R.T.
ISSN
1687-9759 (Electronic)
ISSN-L
1687-9740
Statut éditorial
Publié
Date de publication
2012
Volume
2012
Pages
527891
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish. pdf type: clinical study
Résumé
Objectives: To study the outcome of disconnective epilepsy surgery for intractable hemispheric and sub-hemispheric pediatric epilepsy. Methods: A retrospective analysis of the epilepsy surgery database was done in all children (age <18 years) who underwent a peri-insular hemispherotomy (PIH) or a peri-insular posterior quadrantectomy (PIPQ) from April 2000 to March 2011. All patients underwent a detailed pre surgical evaluation. Seizure outcome was assessed by the Engel's classification and cognitive skills by appropriate measures of intelligence that were repeated annually. Results: There were 34 patients in all. Epilepsy was due to Rasmussen's encephalitis (RE), Infantile hemiplegia seizure syndrome (IHSS), Hemimegalencephaly (HM), Sturge Weber syndrome (SWS) and due to post encephalitic sequelae (PES). Twenty seven (79.4%) patients underwent PIH and seven (20.6%) underwent PIPQ. The mean follow up was 30.5 months. At the last follow up, 31 (91.1%) were seizure free. The age of seizure onset and etiology of the disease causing epilepsy were predictors of a Class I seizure outcome. Conclusions: There is an excellent seizure outcome following disconnective epilepsy surgery for intractable hemispheric and subhemispheric pediatric epilepsy. An older age of seizure onset, RE, SWS and PES were good predictors of a Class I seizure outcome.
Pubmed
Création de la notice
04/02/2014 21:00
Dernière modification de la notice
03/03/2018 13:31
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