Dystonia: pallidal or thalamic target?

Details

Serval ID
serval:BIB_088F063C233E
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Abstract (Abstract): shot summary in a article that contain essentials elements presented during a scientific conference, lecture or from a poster.
Collection
Publications
Institution
Title
Dystonia: pallidal or thalamic target?
Title of the conference
XIVth Congress of the European Society for Stereotactic and Functional Neurosurgery
Author(s)
Villemure JG, Vingerhoets F, Temperli P, Pollo C, Ghika J
Address
London, United Kingdom, on October 25-27, 2000
ISBN
0942-0940
ISSN-L
0001-6268
Publication state
Published
Issued date
2000
Volume
142
Series
Acta Neurochirugica
Pages
1194
Language
english
Abstract
Objective: Determine the e½cacy of bilateral chronic anterior thalamic stimulation in dystonic patients not signi®cantly improved after bilateral Gpi-DBS. Material and Method: 2 patients treated with bilateral Gpi-DBS and showing only modest response underwent bilateral anterior thalamic implantation of stimulating electrodes in the nucleus ventrooralis anterior (VOA: 2 mm anterior to MC, 5 mm superior to AC-PC, 10 mm lateral). Results: Improvement after VOA-DBS was not immediate but followed a silent period of a few weeks in one patient and 5 months in the other. In one patient, wheel-chair bound, the improvement was spectacular with recovery of an harmonious gait and writing, while less dramatic in the other and still ongoing, with loss of dystonic postures of the feet and reduced athetotic movements. Conclusion: Chronic bilateral stimulation of e¨erent pallidal pathways going through the thalamus, speci®cally the VOA, is e¨ective in improving motor function in dystonic patients where Gpi-DBS does not produce signi®cant improvement.
Create date
12/12/2013 0:09
Last modification date
20/08/2019 13:30
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