Swiss guidelines have been published recently for Lyme disease, but three other zoonoses have motivated a particular attention lately because they cause or might cause illnesses in Switzerland. The incidence of tick-borne encephalitis is clearly increasing since 2004. The vaccination of persons living or residing temporally in risk areas is now routinely recommended. Although eradicated in wild mammals since 1996, rabies still constitutes a threat through bats and illegally imported pets. The epidemiology of echinococcosis is influenced by the increase in fox populations in urban areas. This could result in a higher prevalence of the disease in dogs and thus a higher risk of exposure for humans.