When all hypotheses are right: a multifocal account of dyslexia.

Détails

ID Serval
serval:BIB_062B70CFAED5
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
When all hypotheses are right: a multifocal account of dyslexia.
Périodique
Human Brain Mapping
Auteur(s)
Pernet C., Andersson J., Paulesu E., Demonet J.F.
ISSN
1097-0193 (Electronic)
ISSN-L
1065-9471
Statut éditorial
Publié
Date de publication
2009
Peer-reviewed
Oui
Volume
30
Numéro
7
Pages
2278-2292
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish. PDF type: Research Article
Résumé
Many hypotheses have been proposed about the brain underpinnings of developmental dyslexia, but none of them accommodates the variable deficits observed. To address the issue of anatomical deficits in dyslexia; total and partial volumes, lateralization indices (LI), and local gray matter volumes (LGMV) were measured. Analyses were performed in large samples of control and dyslexic subjects, and in correlation with their performance on phonological, reading, and spelling tests. Results indicate an absence of net differences in terms of volumes but significant continuities and discontinuities between groups in their correlations between LI, LGMV, and performances. Structural connectivity also highlighted correlations between areas showing (dis)continuities between control and dyslexic subjects. Overall, our data put forward the idea of a multifocal brain abnormalities in dyslexia with a major implication of the left superior temporal gyrus, occipital-temporal cortices, and lateral/medial cerebellum, which could account for the diverse deficits predicted by the different theories.
Mots-clé
Adult, Analysis of Variance, Brain/pathology, Dyslexia/pathology, Dyslexia/psychology, Female, Humans, Language Tests, Magnetic Resonance Imaging, Male, Neural Pathways/pathology, Neuropsychological Tests, Organ Size, Phonetics, Reaction Time, Reading, Regression Analysis, Writing
Pubmed
Web of science
Création de la notice
24/03/2013 20:16
Dernière modification de la notice
20/08/2019 13:28
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