In the history of quantum physics several no-go theorems have been proved, and many of them have played a central role in the development of the theory, such as Bell’s or the Kochen–Specker theorem. A recent paper by F. Laudisa has raised reasonable doubts concerning the strategy followed in proving some of these results, since they rely on the standard framework of quantum mechanics, a theory that presents several ontological problems. The aim of this paper is twofold: on the one hand, I intend to reinforce Laudisa’s methodological point by critically discussing Malament’s theorem in the context of the philosophical foundation of quantum field theory; secondly, I rehabilitate Gisin’s theorem showing that Laudisa’s concerns do not apply to it.