Molecular phylogenetic evidence for an extracellular Cu Zn superoxide dismutase gene in insects

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Ressource 1Télécharger: BIB_04C401A4A204.P001.pdf (302.47 [Ko])
Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_04C401A4A204
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Molecular phylogenetic evidence for an extracellular Cu Zn superoxide dismutase gene in insects
Périodique
Insect Molecular Biology
Auteur(s)
Parker  J. D., Parker  K. M., Keller  L.
ISSN
0962-1075
Statut éditorial
Publié
Date de publication
12/2004
Peer-reviewed
Oui
Volume
13
Numéro
6
Pages
587-94
Notes
Comparative Study Journal Article Research Support, Non-U.S. Gov't --- Old month value: Dec
Résumé
Representatives of three ancient gene families of the antioxidant enzyme superoxide dismutase (SOD) can be found in most metazoans. In mammals and Caenorhabditis elegans, there is at least one gene each of the cytoplasmic, mitochondrial and extracellular lineages of SOD genes. The cytoplasmic SOD was one of the first enzymes to be implicated in ageing due to its protection against damaging oxygen free radicals. In contrast to other metazoans, insects were thought to lack a gene for the extracellular SOD. We have cloned and sequenced an SOD mRNA in the ant Lasius niger that appears to belong to this extracellular family. Subsequent searches and analyses of SOD gene sequences in insect databases revealed that insects do indeed express all three SOD genes including the extracellular form. We conclude that insects as well as other metazoans appear to have the full repertoire of the three families of SOD.
Mots-clé
Amino Acid Sequence Animals Base Sequence Bayes Theorem DNA Primers Extracellular Space/*metabolism Insects/*genetics/metabolism Models, Genetic Molecular Sequence Data Nucleic Acid Amplification Techniques *Phylogeny Sequence Alignment Sequence Analysis, DNA Superoxide Dismutase/*genetics/metabolism
Pubmed
Web of science
Création de la notice
24/01/2008 19:39
Dernière modification de la notice
03/03/2018 13:22
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