Association of disclosure of HIV status with medication adherence.

Details

Serval ID
serval:BIB_04BDCF523FA8
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Association of disclosure of HIV status with medication adherence.
Journal
Patient education and counseling
Author(s)
Rotzinger A., Locatelli I., Reymermier M., Amico S., Bugnon O., Cavassini M., Schneider M.P.
ISSN
1873-5134 (Electronic)
ISSN-L
0738-3991
Publication state
Published
Issued date
08/2016
Peer-reviewed
Oui
Volume
99
Number
8
Pages
1413-1420
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Disclosure may affect adherence to antiretroviral treatment. In a medication adherence program, this cross-sectional study describes disclosure, perceived reaction after disclosure, living situations, and the relationship of disclosure with antiretroviral adherence.
A combination of a questionnaire to measure disclosure and longitudinal electronic monitoring of medication adherence was used.
A total of 103 out of 159 eligible patients gave informed consent. The characteristics differed between participants and nonparticipants (race, education, sexual orientation, medication adherence). Thirteen participants did not disclose their HIV status. Seventy-three (81%) participants judged the reaction after disclosure positive. Among the 62 participants cohabiting, 52% disclosed to all co-residents. Adherence was high (median 100%). HIV disclosure was negatively associated with adherence, when disclosing to the mother (OR=2.46, p-value=0.086) and to siblings (OR=2.89, p-value=0.029). Living alone was associated to a lower adherence than cohabitation (Rate Ratio=1.42, p-value=0.007).
HIV disclosure and adherence are sensitive issues, which may explain the reason for refusal. Nonparticipants may be those with the most difficulties disclosing.
An unbiased collection of sensitive information, as HIV disclosure, is a difficult task. A cohort design, with research data collected systematically by a trusted healthcare provider, may better describe the association between adherence and disclosure.

Keywords
Adult, Anti-HIV Agents/therapeutic use, Cross-Sectional Studies, Female, HIV Infections/drug therapy, HIV Infections/psychology, HIV Seropositivity/psychology, Humans, Logistic Models, Longitudinal Studies, Male, Medication Adherence, Self Disclosure, Social Stigma, Socioeconomic Factors, Surveys and Questionnaires, Switzerland, Truth Disclosure, Disclosure, HIV, Medication adherence, Refusal to participate, Social support
Pubmed
Web of science
Create date
14/04/2016 16:44
Last modification date
20/08/2019 12:26
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