In vivo endoscopic tissue diagnostics based on spectroscopic absorption, scattering, and phase function properties

Détails

ID Serval
serval:BIB_04523A8171F5
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
In vivo endoscopic tissue diagnostics based on spectroscopic absorption, scattering, and phase function properties
Périodique
Journal of Biomedical Optics
Auteur(s)
Thueler Philippe, and charvet Igor, Bevilacqua Frederic, Ghislain M. St. , Ory G., and Marquet Pierre, Meda Pablo, Vermeulen Ben, Depeursinge Christian
ISSN
1083-3668
Statut éditorial
Publié
Date de publication
2003
Peer-reviewed
Oui
Volume
8
Numéro
3
Pages
495-503
Langue
anglais
Notes
SAPHIRID:67363
Résumé
A fast spectroscopic system for superficial and local determination of the absorption and scattering properties of tissue (480 to 950 nm) is described. The probe can be used in the working channel of an endoscope. The scattering properties include the reduced scattering coefficient and a parameter of the phase function called gamma, which depends on its first two moments. The inverse problem algorithm is based on the fit of absolute reflectance measurements to cubic B-spline functions derived from the interpolation of a set of Monte Carlo simulations. The algorithm's robustness was tested with simulations altered with various amounts of noise. The method was also assessed on tissue phantoms of known optical properties. Finally, clinical measurements performed endoscopically in vivo in the stomach of human subjects are presented. The absorption and scattering properties were found to be significantly different in the antrum and in the fundus and are correlated with histopathologic observations. The method and the instrument show promise for noninvasive tissue diagnostics of various epithelia. (c) 2003 Society of Photo-Optical Instrumentation Engineers.
Pubmed
Web of science
Création de la notice
10/03/2008 16:40
Dernière modification de la notice
20/08/2019 12:26
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