Quantification of aortic flow by phase-contrast magnetic resonance in patients with bicuspid aortic valve.

Détails

Ressource 1Télécharger: BIB_043B5D0A4554.P001.pdf (583.40 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_043B5D0A4554
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Quantification of aortic flow by phase-contrast magnetic resonance in patients with bicuspid aortic valve.
Périodique
European Heart Journal Cardiovascular Imaging
Auteur(s)
Muzzarelli S., Monney P., O'Brien K., Faletra F., Moccetti T., Vogt P., Schwitter J.
ISSN
2047-2412 (Electronic)
Statut éditorial
Publié
Date de publication
2014
Volume
15
Numéro
1
Pages
77-84
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
AIMS: Bicuspid aortic valve (BAV) causes complex flow patterns in the ascending aorta (AAo), which may compromise the accuracy of flow measurement by phase-contrast magnetic resonance (PC-MR). Therefore, we aimed to assess and compare the accuracy of forward flow measurement in the AAo, where complex flow is more dominant in BAV patients, with flow quantification in the left ventricular outflow tract (LVOT) and the aortic valve orifice (AV), where complex flow is less important, in BAV patients and controls.
METHODS AND RESULTS: Flow was measured by PC-MR in 22 BAV patients and 20 controls at the following positions: (i) LVOT, (ii) AV, and (iii) AAo, and compared with the left ventricular stroke volume (LVSV). The correlation between the LVSV and the forward flow in the LVOT, the AV, and the AAo was good in BAV patients (r = 0.97/0.96/0.93; P < 0.01) and controls (r = 0.96/0.93/0.93; P < 0.01). However, in relation with the LVSV, the forward flow in the AAo was mildly underestimated in controls and much more in BAV patients [median (inter-quartile range): 9% (4%/15%) vs. 22% (8%/30%); P < 0.01]. This was not the case in the LVOT and the AV. The severity of flow underestimation in the AAo was associated with flow eccentricity.
CONCLUSION: Flow measurement in the AAo leads to an underestimation of the forward flow in BAV patients. Measurement in the LVOT or the AV, where complex flow is less prominent, is an alternative means for quantifying the systolic forward flow in BAV patients.
Pubmed
Web of science
Open Access
Oui
Création de la notice
24/01/2014 19:32
Dernière modification de la notice
20/08/2019 13:26
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