Changing trends in end-stage renal disease patients with diabetes.

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State: Public
Version: Final published version
Serval ID
serval:BIB_03D3BBAF84B1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Changing trends in end-stage renal disease patients with diabetes.
Journal
Swiss medical weekly
Author(s)
Lu Y., Stamm C., Nobre D., Pruijm M., Teta D., Cherpillod A., Halabi G., Phan O., Fumeaux Z., Bullani R., Gauthier T., Mathieu C., Burnier M., Zanchi A.
ISSN
1424-3997 (Electronic)
ISSN-L
0036-7672
Publication state
Published
Issued date
11/07/2017
Peer-reviewed
Oui
Volume
147
Pages
w14458
Language
english
Notes
Publication types: Journal Article ; Observational Study
Publication Status: epublish
Abstract
Worldwide, diabetes has become the most common cause of end-stage renal disease (ESRD), yet Swiss data are largely lacking.
This observational study examined ESRD patients with diabetes mellitus (ESRD-DM) at end of 2009 and 2014. The prevalence and characteristics of ESRD-DM patients were collected in all dialysis facilities in the Canton of Vaud of Switzerland in 2009 and in 2014, and the 5-year mortality rate was assessed.
A total of 107 and 140 ESRD-DM patients underwent dialysis at end of 2009 and 2014, respectively. Within the 5-year period a total of 167 incidental ESRD-DM patients required dialysis, corresponding to an estimated incidental rate of 0.84/1000 person-years in the diabetic population. In 2009, all patients with ESRD-DM underwent haemodialysis, decreasing to 96.2% in 2014, with 3.8% on peritoneal dialysis. Age, sex, body mass index, type of diabetes, duration of diabetes, cause of ESRD, dialysis duration, dialysis frequency, vascular access, and glycosylated haemoglobin levels did not differ between 2009 and 2014. In 2014, macrovascular comorbidity was reported more often than in 2009, but not amputations. Haemoglobin level decreased significantly from 117.9 g/l to 112.3 g/l. Calcium-containing phosphate binder and angiotensin-converting enzyme inhibitor use significantly decreased, whereas iron therapy significantly increased with time. The 5-year mortality rate was 61.7%. Five-year survivors were significantly younger and had a higher body mass index.
The growing prevalence of ESRD-DM emphasises that prevention of chronic kidney disease and its progression should be a public health priority in Switzerland.

Keywords
Aged, Diabetic Nephropathies/complications, Diabetic Nephropathies/epidemiology, Diabetic Nephropathies/therapy, Female, Humans, Kidney Failure, Chronic/epidemiology, Kidney Failure, Chronic/etiology, Kidney Failure, Chronic/therapy, Male, Middle Aged, Prevalence, Renal Dialysis/statistics & numerical data, Switzerland/epidemiology
Pubmed
Web of science
Open Access
Yes
Create date
03/08/2017 12:42
Last modification date
20/08/2019 12:25
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