Genomic islands and the evolution of catabolic pathways in bacteria.

Détails

ID Serval
serval:BIB_032E4BAFD3C5
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Genomic islands and the evolution of catabolic pathways in bacteria.
Périodique
Current Opinion in Biotechnology
Auteur(s)
van der Meer J.R., Sentchilo V.
ISSN
0958-1669 (Print)
ISSN-L
0958-1669
Statut éditorial
Publié
Date de publication
2003
Volume
14
Numéro
3
Pages
248-254
Langue
anglais
Résumé
Genes for the degradation of organic pollutants have usually been allocated to plasmid DNAs in bacteria or considered non-mobile when detected in the chromosome. New discoveries have shown that catabolic genes can also be part of so-called integrative and conjugative elements (ICElands), a group of mobile DNA elements also known as genomic islands and conjugative transposons. One such ICEland is the clc element for chlorobenzoate and chlorocatechol degradation in Pseudomonas sp. strain B13. Genome comparisons and genetic data on integrase functioning reveal that the clc element and several other unclassified ICElands belong to a group of elements with conserved features. The clc element is unique among them in carrying the genetic information for several degradation pathways, whereas the others give evidence for pathogenicity functions. Many more such elements may exist, bridging the gap between pathogenicity and degradation functions.
Mots-clé
Catalysis, DNA Transposable Elements, Energy Metabolism, Environmental Pollutants/metabolism, Evolution, Molecular, Gene Expression Regulation, Bacterial/physiology, Genes, Regulator, Genomic Islands/genetics, Pseudomonas/genetics, Pseudomonas/metabolism
Pubmed
Web of science
Création de la notice
21/01/2008 14:36
Dernière modification de la notice
03/03/2018 13:19
Données d'usage