Coffee and tea intake and risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium.

Détails

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Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_02D2258E8D0E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Coffee and tea intake and risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium.
Périodique
Cancer Epidemiology, Biomarkers and Prevention
Auteur(s)
Galeone Carlotta, Tavani Alessandra, Pelucchi Claudio, Turati Federica, Winn Deborah M., Levi Fabio, Yu Guo-Pei, Morgenstern Hal, Kelsey Karl, Dal Maso Luigino, Purdue Mark P., McClean Michael, Talamini Renato, Hayes Richard B., Franceschi Silvia, Schantz Stimson, Zhang Zuo-Feng, Ferro Gilles, Chuang Shu-Chun, Boffetta Paolo, La Vecchia Carlo, Hashibe Mia
ISSN
1538-7755[electronic], 1055-9965[linking]
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
19
Numéro
7
Pages
1723-1736
Langue
anglais
Résumé
BACKGROUND: Only a few studies have explored the relation between coffee and tea intake and head and neck cancers, with inconsistent results. METHODS: We pooled individual-level data from nine case-control studies of head and neck cancers, including 5,139 cases and 9,028 controls. Logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (95% CI), adjusting for potential confounders. RESULTS: Caffeinated coffee intake was inversely related with the risk of cancer of the oral cavity and pharynx: the ORs were 0.96 (95% CI, 0.94-0.98) for an increment of 1 cup per day and 0.61 (95% CI, 0.47-0.80) in drinkers of >4 cups per day versus nondrinkers. This latter estimate was consistent for different anatomic sites (OR, 0.46; 95% CI, 0.30-0.71 for oral cavity; OR, 0.58; 95% CI, 0.41-0.82 for oropharynx/hypopharynx; and OR, 0.61; 95% CI, 0.37-1.01 for oral cavity/pharynx not otherwise specified) and across strata of selected covariates. No association of caffeinated coffee drinking was found with laryngeal cancer (OR, 0.96; 95% CI, 0.64-1.45 in drinkers of >4 cups per day versus nondrinkers). Data on decaffeinated coffee were too sparse for detailed analysis, but indicated no increased risk. Tea intake was not associated with head and neck cancer risk (OR, 0.99; 95% CI, 0.89-1.11 for drinkers versus nondrinkers). CONCLUSIONS: This pooled analysis of case-control studies supports the hypothesis of an inverse association between caffeinated coffee drinking and risk of cancer of the oral cavity and pharynx. IMPACT: Given widespread use of coffee and the relatively high incidence and low survival of head and neck cancers, the observed inverse association may have appreciable public health relevance.
Mots-clé
Adolescent, Adult, Aged, Caffeine/administration & dosage, Caffeine/adverse effects, Case-Control Studies, Coffee/adverse effects, Cohort Studies, Female, Head and Neck Neoplasms/chemically induced, Head and Neck Neoplasms/epidemiology, Humans, Logistic Models, Male, Middle Aged, Mouth Neoplasms/chemically induced, Mouth Neoplasms/epidemiology, Pharyngeal Neoplasms/chemically induced, Pharyngeal Neoplasms/epidemiology, Risk Factors, Tea/adverse effects, Young Adult
Pubmed
Web of science
Open Access
Oui
Création de la notice
05/11/2010 12:08
Dernière modification de la notice
20/08/2019 13:24
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