Un reseau pour la recherche du ganglion sentinelle du cancer du sein. [Network for sentinel lymph node research in breast cancer]

Details

Serval ID
serval:BIB_02932D9F1BE1
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Un reseau pour la recherche du ganglion sentinelle du cancer du sein. [Network for sentinel lymph node research in breast cancer]
Journal
Revue Médicale de la Suisse Romande
Author(s)
Delaloye J. F., Monod J. F., Friedli A., Burgener F., Stalder J. B., Fiche M., De Grandi P., Bischof Delaloye A.
ISSN
0035-3655 (Print)
Publication state
Published
Issued date
05/2003
Volume
123
Number
5
Pages
299-302
Language
french
Notes
English Abstract Journal Article --- Old month value: May
Abstract
AIMS: The goals of this paper were to determine the accuracy of the sentinel node in predicting axillary nodal status and to evaluate the feasibility of incorporating sentinel node biopsy into a general practice. METHODS: Between June 1999 and February 2003, 304 patients with clinically T0-T2[< 3 cm] M0 breast cancer underwent sentinel node biopsy. Both lymphoscintigraphy and blue dye were used to guide this biopsy. The procedure was followed by a complete axillary dissection in the first patients and when the sentinel node was positive. Sentinel nodes were evaluated using serial levels of hematoxylin eosin staining, and cytokeratin immunohistochemistry. RESULTS: The overall sentinel node detection rate was 99% (301 of 304 patients). The accuracy of the identification in operating room was 98% (296 of 301 patients). The sentinel node was involved in 75 patients (25%): metastases (38 patients), micrometastases (32 patients) and isolated tumor cells (5 patients). The false negative rate was 0% and the negative predictive value 100%. CONCLUSION: Our results support that the sentinel node biopsy is an accurate predictor of axillary nodal status in patients with early breast cancer and implementing a network greatly facilitates its' discovery.
Keywords
Adult Aged Aged, 80 and over Breast Neoplasms/*pathology Female Humans Middle Aged *Sentinel Lymph Node Biopsy
Pubmed
Create date
25/01/2008 15:42
Last modification date
20/08/2019 12:24
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