Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
The metabolic effects of limbic leucotomy in Gilles de la Tourette syndrome.
Journal of Neurology, Neurosurgery, and Psychiatry
Publication types: Case Reports ; Journal ArticlePublication Status: ppublish
Regional cerebral oxygen metabolism was measured before and after limbic leucotomy in a patient with Gilles de la Tourette syndrome, obsessive compulsive disorder, and obsessional slowness. The preoperative scan showed hypermetabolism in the caudate nuclei, which normalised after operation. It is proposed that the beneficial effects of this operation on both tics and obsessive compulsive behaviour are mediated by disruption of abnormal neural activity in basal ganglia-thalamocortical loops.
Brain/metabolism, Electrocoagulation, Humans, Limbic System/surgery, Male, Middle Aged, Oxygen/metabolism, Tomography, Emission-Computed, Tourette Syndrome/metabolism, Tourette Syndrome/surgery
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