Uveitis in der Kindheit: eine epidemiologische Studie über 20 Jahre [Epidemiology of Childhood Uveitis in a Tertiary Care Center: A 20-Year Study]
Details
Serval ID
serval:BIB_022FC640ABA1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Uveitis in der Kindheit: eine epidemiologische Studie über 20 Jahre [Epidemiology of Childhood Uveitis in a Tertiary Care Center: A 20-Year Study]
Journal
Klinische Monatsblatter fur Augenheilkunde
ISSN
1439-3999 (Electronic)
ISSN-L
0023-2165
Publication state
Published
Issued date
04/2021
Peer-reviewed
Oui
Volume
238
Number
4
Pages
469-473
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
To investigate demographics and causes of pediatric uveitis in a Swiss tertiary reference center over a 20-year period.
Retrospective cohort study on patients with uveitis aged less than 16 years seen at Jules-Gonin Eye Hospital between 1 January 2000 and 31 December 2019.
Out of 2846 patients with uveitis seen in the Jules-Gonin Eye Hospital Ocular Immune-Infectiology Department, 317 (11.1%) were under 16 years of age and were included in this study. Median age at onset of the uveitis was 8.9 years (range 0 - 16). Anterior uveitis was the most frequent presentation (45.1%) followed by posterior uveitis in 26.2%, intermediate uveitis in 23.3%, and panuveitis in 5.4%. The inflammation was most frequently bilateral and non-granulomatous. A systemic inflammatory disease was found in 34% of the cases and an infectious cause in 24%.
The repartition of the location of the uveitis was similar to previous reports from Western countries. Uveitis in juvenile idiopathic arthritis is the most frequent etiology related to a systemic disease in children. An infectious cause was found in 24% of our patients, which is a greater proportion than in adult cohorts.
Retrospective cohort study on patients with uveitis aged less than 16 years seen at Jules-Gonin Eye Hospital between 1 January 2000 and 31 December 2019.
Out of 2846 patients with uveitis seen in the Jules-Gonin Eye Hospital Ocular Immune-Infectiology Department, 317 (11.1%) were under 16 years of age and were included in this study. Median age at onset of the uveitis was 8.9 years (range 0 - 16). Anterior uveitis was the most frequent presentation (45.1%) followed by posterior uveitis in 26.2%, intermediate uveitis in 23.3%, and panuveitis in 5.4%. The inflammation was most frequently bilateral and non-granulomatous. A systemic inflammatory disease was found in 34% of the cases and an infectious cause in 24%.
The repartition of the location of the uveitis was similar to previous reports from Western countries. Uveitis in juvenile idiopathic arthritis is the most frequent etiology related to a systemic disease in children. An infectious cause was found in 24% of our patients, which is a greater proportion than in adult cohorts.
Keywords
Adolescent, Adult, Aged, Child, Child, Preschool, Humans, Infant, Infant, Newborn, Retrospective Studies, Tertiary Care Centers, Uveitis/diagnosis, Uveitis/epidemiology, Uveitis, Anterior, Uveitis, Posterior
Pubmed
Web of science
Create date
27/04/2021 13:51
Last modification date
29/05/2021 5:31