Long term followup of photorefractive keratectomy with adjuvant use of mitomycin C.
Details
Serval ID
serval:BIB_021744C22435
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Long term followup of photorefractive keratectomy with adjuvant use of mitomycin C.
Journal
Journal of ophthalmology
ISSN
2090-004X (Print)
ISSN-L
2090-004X
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
2014
Pages
821920
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
Purpose. To study the long term refractive and visual outcomes of photorefractive keratectomy (PRK) with intraoperative application of mitomycin C (MMC). Methods. This study included 37 eyes who received myopic PRK; after photoablation, a sponge soaked in 0.02% MMC solution was applied in all corneas for 2 minutes. Efficacy, safety, predictability, and stability of PRK MMC were evaluated. Endothelial cell density was evaluated at the last postoperative interval. Results. Mean preoperative spherical equivalent (SEQ) was -6.03 ± 1.87 D (diopters) and reduced to -0.09 ± 0.53 D at the last postoperative examination. Mean followup was 44.73 ± 18.24 months. All the eyes were in the ±1.00 D of attempted versus achieved SEQ at the one-year follow-up interval. Furthermore, 95% of the eyes did not lose lines or gained 1 to 2 lines of CDVA, while 5% lost 1 line. At the third postoperative month, 89% of the eyes either were clear or had trace haze, while 4 eyes had mild haze; by the 12-month postoperative interval, none of the eyes demonstrated haze. Mean endothelial cell density (ECD) at the last postoperative interval was 2658 ± 153 cells/mm(2). Conclusions. PRK, with intraoperative use of MMC, demonstrates stable refractive and visual outcomes up to 44 months after surgery.
Pubmed
Web of science
Open Access
Yes
Create date
30/09/2019 17:22
Last modification date
13/01/2021 8:08