Pulmonary complications after liver transplantation in children: the Swiss national center experience

Details

Serval ID
serval:BIB_01AA1EE04CDF
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Abstract (Abstract): shot summary in a article that contain essentials elements presented during a scientific conference, lecture or from a poster.
Collection
Publications
Title
Pulmonary complications after liver transplantation in children: the Swiss national center experience
Title of the conference
7th Congress on Pediatric Transplantation : Discover the Unexpected
Author(s)
McLin VA, Blanchon S$ , Ruchonnet-Metrailler I, Luethold S Wildhaber BE, Argiroffo CB
Address
Warsaw, Poland, July 12-16 2013
ISBN
1397-3142
Publication state
Published
Issued date
2013
Volume
17
Series
Pediatric Transplantation
Pages
84-85
Language
english
Notes
Meeting Abstract: 175
Abstract
PURPOSE: Liver transplantation (LT) has become the treatment of end-stage liver disease. No recent data are available on pulmonary complication after LT in children, despite advances in LT management. As our center is the LT national center, we studied pediatric pulmonary complications, in order to identify pre and per operative risk factors.
METHOD: We retrospectively included all children requiring LT from 2000 to 2011. We recorded patient and donor characteristics, cardio-pulmonary evaluation, operative data, post-operative management and outcome.
RESULTS: 72 children underwent 82 LT (3.4 ±4.6 years old), because of biliary atresia (n=32), other cholestasis (n=16), fulminant hepatic failure (n=6), metabolic disorder (n=14), neoplasia (n=3), other cirrhosis (n=7) and graft rejection (n=4). To date, data from 37 LT were recorded. Pre-operative assessment showed portal hypertension (n=22), hepato-pulmonary syndrome (n=1), encephalopathy (n=9), ascites (n=24) renal failure (n=4) and no pulmonary hypertension. Early post operative (<1 month) lung assessment showed pulmonary edema (n=16), pleural effusion (n=22, including 5 requiring drain), atelectasis (n=14), infection (n=3), but no pulmonary hemorrhage, pneumothorax, or diaphragmatic paralysis. No delayed (1-3 months) lung complication occurred. In long term (>3 months) pulmonary follow-up, pneumonia (n=3), extrinsic alveolitis (n=1), central and obstructive apnea (n=1) were observed. 4 patients died but not because of lung-related cause.
CONCLUSION: The incidence of pulmonary complications after LT seems decrease compared to older published cohorts. Analysis of potential risk factors will improve our understanding of how to prevent them.
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Create date
21/02/2015 12:04
Last modification date
20/08/2019 13:23
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