Influence of transport and time on blood variables commonly measured for the athlete biological passport.
Details
Serval ID
serval:BIB_00B038C43440
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Influence of transport and time on blood variables commonly measured for the athlete biological passport.
Journal
Drug testing and analysis
ISSN
1942-7611 (Electronic)
ISSN-L
1942-7603
Publication state
Published
Issued date
02/2016
Peer-reviewed
Oui
Volume
8
Number
2
Pages
199-207
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Abstract
Some recent studies have characterized the stability of blood variables commonly measured for the Athlete Biological Passport. The aim of this study was to characterize the impact of different shipments conditions and the quality of the results returned by the haematological analyzer. Twenty-two healthy male subjects provided five EDTA tubes each. Four shipment conditions (24, 36, 48, 72 h) under refrigerated conditions were tested and compared to a set of samples left in the laboratory also under refrigerated conditions (group control). All measurements were conducted using two Sysmex XT-2000i analyzers. Haemoglobin concentration, reticulocytes percentage, and OFF-score numerical data were the same for samples analyzed just after collection and after a shipment under refrigerated conditions up to 72 h. Detailed information reported especially by the differential (DIFF) channel scatterplot of the Sysmex XT-2000i indicated that there were signs of blood deterioration, but were not of relevance for the variables used in the Athlete Biological Passport. As long as the cold chain is guaranteed, the time delay between the collection and the analyses of blood variables can be extended.
Keywords
Adult, Algorithms, Athletes, Blood Chemical Analysis/methods, Blood Chemical Analysis/standards, Doping in Sports/methods, Erythrocyte Count, Erythrocytes/chemistry, Hemoglobins/analysis, Humans, Male, Refrigeration, Reproducibility of Results, Reticulocyte Count, Specimen Handling, Time Factors, Young Adult
Pubmed
Web of science
Create date
05/05/2015 7:47
Last modification date
20/08/2019 12:22