Desensitization of thermal hyperemia in the skin is reproducible.

Détails

ID Serval
serval:BIB_005E650DA803
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Desensitization of thermal hyperemia in the skin is reproducible.
Périodique
Microcirculation
Auteur(s)
Frantz J., Engelberger R.P., Liaudet L., Mazzolai L., Waeber B., Feihl F.
ISSN
1549-8719 (Electronic)
ISSN-L
1073-9688
Statut éditorial
Publié
Date de publication
2012
Peer-reviewed
Oui
Volume
19
Numéro
1
Pages
78-85
Langue
anglais
Notes
Publication types: Clinical Trial ; Journal Article
Publication Status: ppublish
Résumé
OBJECTIVE: Local heating increases skin blood flow SkBF (thermal hyperemia). In a previous study, we reported that a first local thermal stimulus could attenuate the hyperemic response to a second one applied later on the same skin spot, a phenomenon that we termed desensitization. However, other studies found no evidence for desensitization in similar conditions. The aim of the present work was to test whether it was related to differences in instrumentation.
METHODS: Twenty-eight healthy young males were studied. Two pairs of heating chambers, one custom-made (our study) and one commercial (other groups), were affixed to forearm skin. SkBF was measured with single-point laser-Doppler flowmetry (LDF) (780nm) in one pair, and laser-Doppler imaging (LDI) (633nm) in the other. A temperature step from 34 to 41°C, was applied for 30minutes and repeated after two hours.
RESULTS: During the second thermal challenge, the plateau SkBF was lower than during the first thermal and was observed with each of the four combinations of SkBF measurement techniques and heating equipment (p<0.05 for all conditions, range -9% to -16% of the initial value).
CONCLUSION: Desensitization of thermal hyperemia is not specific to peculiar operating conditions.
Mots-clé
Adolescent, Adult, Hot Temperature, Humans, Hyperemia/physiopathology, Laser-Doppler Flowmetry/methods, Male, Reproducibility of Results, Skin/blood supply, Time Factors
Pubmed
Web of science
Création de la notice
06/02/2012 17:46
Dernière modification de la notice
03/03/2018 13:11
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