Toxoplasmic retinochoroiditis: resolution without treatment of the perilesional satellite dark dots seen by indocyanine green angiography

Details

Serval ID
serval:BIB_0049065170BA
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Toxoplasmic retinochoroiditis: resolution without treatment of the perilesional satellite dark dots seen by indocyanine green angiography
Journal
Graefe's Archive for Clinical and Experimental Ophthalmology
Author(s)
Guex-Crosier  Y., Auer  C., Bernasconi  O., Herbort  C. P.
ISSN
0721-832X (Print)
Publication state
Published
Issued date
06/1998
Volume
236
Number
6
Pages
476-8
Notes
Case Reports
Journal Article --- Old month value: Jun
Abstract
PURPOSE: Satellite dark dots (SDD) seen by indocyanine green angiography (ICGA) around the main retinochoroiditis focus are described in 75% of cases. Whether SDDs represent subclinical infectious foci or just a perilesional inflammatory reaction is not known. The purpose here was to report a case giving additional information on this question. METHODS: We analysed the evolution of ICGA SDDs in a patient with recurrent toxoplasmic retinochoroiditis who received no antitoxoplasmic treatment because the lesion was located outside the areas where treatment is classically recommended. RESULTS: The patient had a recurrence of retinochoroiditis on the nasal aspect of the disc about 2 disc diameters away from the disc. It was decided to observe the recurrence before introducing treatment. Diminution of SDDs occurred by 3 weeks after the initial ICGA, and complete resolution was observed on a follow-up ICG angiogram obtained 8 weeks after the initial visit. CONCLUSION: Resolution of ICGA SDDs in toxoplasmic retinochoroiditis seems to occurring a similar fashion whether or not the retinochoroiditis is treated by anti-toxoplasmic drugs, indicating that SDDs probably represent a non-infectious perilesional inflammatory reaction.
Keywords
Acute Disease Adult Animals Antibodies, Protozoan/analysis Chorioretinitis/diagnosis/etiology/*physiopathology Choroid/pathology Coloring Agents/*diagnostic use *Fluorescein Angiography Follow-Up Studies Fundus Oculi Humans Indocyanine Green/*diagnostic use Male Recurrence Remission, Spontaneous Retina/pathology Toxoplasma/immunology Toxoplasmosis, Ocular/complications/diagnosis/*physiopathology
Pubmed
Web of science
Create date
28/01/2008 13:45
Last modification date
20/08/2019 13:22
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