Physico-chemical characterization and oxidative reactivity evaluation of aged brake wear particles

Détails

Ressource 1Télécharger: BIB_00285E7097E9.P001.pdf (539.73 [Ko])
Etat: Serval
Version: Final published version
ID Serval
serval:BIB_00285E7097E9
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Physico-chemical characterization and oxidative reactivity evaluation of aged brake wear particles
Périodique
Aerosol Science and Technology : the journal of the American Association for Aerosol Research
Auteur(s)
Zhao Jiayuan, Lewinski Nastassja, Riediker Michael
ISSN
0278-6826
ISSN-L
ESSN: 1521-7388
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
49
Numéro
2
Pages
65-74
Langue
anglais
Résumé
Brake wear dust is a significant component of traffic emissions and has been linked to adverse health effects. Previous research found a strong oxidative stress response in cells exposed to freshly generated brake wear dust. We characterized aged dust collected from passenger vehicles, using microscopy and elemental analyses. Reactive oxygen species (ROS) generation was measured with acellular and cellular assays using 2′7-dichlorodihydrofluorescein dye. Microscopy analyses revealed samples to be heterogeneous particle mixtures with few nanoparticles detected. Several metals, primarily iron and copper, were identified. High oxygen concentrations suggested that the elements were oxidized. ROS were detected in the cell-free fluorescent test, while exposed cells were not dramatically activated by the concentrations used. The fact that aged brake wear samples have lower oxidative stress potential than fresh ones may relate to the highly oxidized or aged state of these particles, as well as their larger size and smaller reactive surface area.
Mots-clé
Reactive Oxygen Species , Nanoparticles , Oxidative Stress , Fluoresceins , Environmental Exposure , Environmental Health
Web of science
Open Access
Oui
Création de la notice
13/02/2015 12:26
Dernière modification de la notice
08/05/2019 13:37
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