A roadmap for driving CAR T cells toward the oncogenic immunopeptidome.

Détails

ID Serval
serval:BIB_FF0839215AF4
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Lettre (letter): communication adressée à l'éditeur.
Collection
Publications
Institution
Titre
A roadmap for driving CAR T cells toward the oncogenic immunopeptidome.
Périodique
Cancer cell
Auteur⸱e⸱s
Irving M., Zoete V., Bassani-Sternberg M., Coukos G.
ISSN
1878-3686 (Electronic)
ISSN-L
1535-6108
Statut éditorial
Publié
Date de publication
10/01/2022
Peer-reviewed
Oui
Volume
40
Numéro
1
Pages
20-22
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
A critical barrier to CAR T cell therapy is the paucity of target antigens that are broadly and stably expressed exclusively in tumors. In their comprehensive multi-omics and pre-clinical study, Yarmarkovich et al. provide proof of principle for the development and efficacy of peptide centric (PC)-CARs targeting the oncogenic immunopeptidome of neuroblastoma.
Pubmed
Web of science
Création de la notice
17/01/2022 9:16
Dernière modification de la notice
02/03/2022 6:34
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