Periprosthetic joint infection: current concepts and outlook.

Détails

ID Serval
serval:BIB_F6773ED4B2F3
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Periprosthetic joint infection: current concepts and outlook.
Périodique
EFORT open reviews
Auteur⸱e⸱s
Izakovicova P., Borens O., Trampuz A.
ISSN
2058-5241 (Print)
ISSN-L
2058-5241
Statut éditorial
Publié
Date de publication
07/2019
Peer-reviewed
Oui
Volume
4
Numéro
7
Pages
482-494
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Résumé
Periprosthetic joint infection (PJI) is a serious complication occurring in 1% to 2% of primary arthroplasties, which is associated with high morbidity and need for complex interdisciplinary treatment strategies.The challenge in the management of PJI is the persistence of micro-organisms on the implant surface in the form of biofilm. Understanding this ability, the phases of biofilm formation, antimicrobial susceptibility and the limitations of host local immune response allows an individual choice of the most suitable treatment.By using diagnostic methods for biofilm detection such as sonication, the sensitivity for diagnosing PJI is increasing, especially in chronic infections caused by low-virulence pathogens.The use of biofilm-active antibiotics enables eradication of micro-organisms in the presence of a foreign body. The total duration of antibiotic treatment following revision surgery should not exceed 12 weeks. Cite this article: EFORT Open Rev 2019;4:482-494. DOI: 10.1302/2058-5241.4.180092.
Mots-clé
arthroplasty, biofilm, diagnosis, periprosthetic joint infection, treatment
Pubmed
Web of science
Open Access
Oui
Création de la notice
31/08/2019 0:21
Dernière modification de la notice
23/04/2024 6:59
Données d'usage