Molar pregnancy with a coexistent fetus after intracytoplasmic sperm injection. A case report

Détails

ID Serval
serval:BIB_F665D9537C50
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Molar pregnancy with a coexistent fetus after intracytoplasmic sperm injection. A case report
Périodique
Journal of Reproductive Medicine
Auteur(s)
Petignat  P., Senn  A., Hohlfeld  P., Blant  S. A., Laurini  R., Germond  M.
ISSN
0024-7758 (Print)
Statut éditorial
Publié
Date de publication
03/2001
Volume
46
Numéro
3
Pages
270-4
Notes
Case Reports
Journal Article
Twin Study --- Old month value: Mar
Résumé
BACKGROUND: Normal fertilization is usually considered to have occurred when two pronculei (2PN) and two polar bodies are observed. Exceptions are the single pronucleated zygote resulting from asynchronous pronuclei. CASE: A 29-year-old woman entered a program of intracytoplasmic sperm injection and embryo transfer because of her husband's oligoasthenoteratozoospermia. Two cleavage-stage embryos (four blastomeres, grade 1 and 2) were obtained from one fertilized oocyte containing distinct 2PN and the other a single pronucleus (1PN). At 15 weeks' gestation the patient developed severe preeclampsia requiring termination of the pregnancy. Histopathologic examination and DNA ploidy by image analysis were consistent with a twin pregnancy combining a complete hydatidiform mole and normal pregnancy. CONCLUSION: We hypothesize that this 1PN was at the origin of the hydatidiform mole. This case highlights the danger of transferring an embryo having 1PN.
Mots-clé
Abortion, Therapeutic Adult Anemia, Hemolytic/complications Embryo/*pathology Female Humans Hydatidiform Mole/complications/*etiology Photomicrography Pre-Eclampsia/complications/therapy Pregnancy *Pregnancy, Multiple *Sperm Injections, Intracytoplasmic Twins *Zygote Intrafallopian Transfer
Pubmed
Web of science
Création de la notice
25/01/2008 12:11
Dernière modification de la notice
20/08/2019 17:22
Données d'usage