Prise en charge du syndrome des ­anticorps antiphospholipides chez l’adulte [Management of the antiphospholipid syndrome in adults]

Détails

ID Serval
serval:BIB_F55407187560
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Prise en charge du syndrome des ­anticorps antiphospholipides chez l’adulte [Management of the antiphospholipid syndrome in adults]
Périodique
Revue medicale suisse
Auteur(s)
Doms J., Horisberger A., Ribi C.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
08/04/2020
Peer-reviewed
Oui
Volume
16
Numéro
689
Pages
670-674
Langue
français
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
The antiphospholipid syndrome (APS) is a complex autoimmune -disease characterized by the expression of antiphospholipid -antibodies (APL) and a variety of clinical presentation. The latest classification defines APS by the occurrence of vascular thrombosis and/or typical obstetrical morbidity together with persistently -detectable APL at least 12 weeks apart. The latest recommendation proposes a risk profile based on the type and titer of APL detected, in order to guide the intensity of prophylactic measures. Based on current knowledge, novel oral anticoagulants should not be used in APS, particularly in patients with a high-risk APL profile or arterial thrombosis. Beyond the mere aspect of anticoagulant treatment, immunomodulatory approaches to the APS such as hydroxychloroquine are under investigation.
Mots-clé
Adult, Antibodies, Antiphospholipid/blood, Anticoagulants/therapeutic use, Antiphospholipid Syndrome/blood, Antiphospholipid Syndrome/complications, Antiphospholipid Syndrome/drug therapy, Female, Humans, Hydroxychloroquine/therapeutic use, Knowledge, Pregnancy, Pregnancy Complications/blood, Pregnancy Complications/drug therapy, Risk Factors, Thrombosis/blood, Thrombosis/drug therapy, Thrombosis/etiology
Pubmed
Création de la notice
25/04/2020 21:45
Dernière modification de la notice
03/07/2020 6:26
Données d'usage