Firing Up Cold Tumors.
Détails
ID Serval
serval:BIB_F50ED56DE9EB
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Firing Up Cold Tumors.
Périodique
Trends in cancer
ISSN
2405-8025 (Electronic)
ISSN-L
2405-8025
Statut éditorial
Publié
Date de publication
09/2019
Peer-reviewed
Oui
Volume
5
Numéro
9
Pages
528-530
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
Elucidating how tumor-intrinsic pathways regulate T cell infiltration in tumors is crucial for developing new therapeutic strategies for immune checkpoint blockade therapy. Here, we review recent progress on how these pathways orchestrate immune status in tumors and discuss the potential interventions for reprogramming the tumor microenvironment for cancer treatment.
Mots-clé
Antineoplastic Agents, Immunological/pharmacology, Antineoplastic Agents, Immunological/therapeutic use, B7-H1 Antigen/antagonists & inhibitors, B7-H1 Antigen/immunology, B7-H1 Antigen/metabolism, Drug Resistance, Neoplasm/drug effects, Drug Resistance, Neoplasm/genetics, Humans, Lymphocytes, Tumor-Infiltrating/drug effects, Lymphocytes, Tumor-Infiltrating/immunology, Lymphocytes, Tumor-Infiltrating/metabolism, Mutation, Neoplasms/drug therapy, Neoplasms/genetics, Neoplasms/immunology, Neoplasms/pathology, Programmed Cell Death 1 Receptor/antagonists & inhibitors, Programmed Cell Death 1 Receptor/immunology, Programmed Cell Death 1 Receptor/metabolism, T-Lymphocytes/drug effects, T-Lymphocytes/immunology, T-Lymphocytes/metabolism, Tumor Escape/drug effects, Tumor Escape/genetics, Tumor Microenvironment/drug effects, Tumor Microenvironment/genetics, Tumor Microenvironment/immunology, Uncoupling Protein 2/metabolism, antitumor immune cycle, conventional type I dendritic cells, immune checkpoint blockade, resistance, tumor microenvironment
Pubmed
Web of science
Création de la notice
13/09/2019 18:54
Dernière modification de la notice
05/09/2020 6:26
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